Driver Chelsie Faulk, 18, of Lady's Island and front-seat passenger Kayleeana Hudson-Banks, 15, of St. Helena died in the accident at about 7:44 p.m., said Beaufort County Coroner Ed Allen.

A 16-year-old girl riding in the car's back seat was airlifted to Memorial University Medical Center in Savannah, according to S.C. Highway Patrol.

Faulk was driving a 2009 Mitsubishi sedan when it veered off the left side of Seaside Road, overturned and struck a tree, according to Highway Patrol. The accident is under investigation and no factors have been established as to its cause, said Lance Cpl. Brent Kelly.

All three girls were wearing seat belts, Kelly said.

Later Saturday, another collision was reported in McCormick County where two Greenwood men died.

Early Sunday, Curtis Fitzgerald Norman, 46, of Rock Hill man died after his car ran off the road, hitting a sign and some trees, officials say. Norman was driving a 2003 Cadillac Escalade south on the highway when he ran off the right side of the road, said Lance Cpl. Scot Edgeworth. He hit a highway sign and some trees and became entrapped in the car.

Officials noted the wet conditions, but did not say if weather contributed to the crash.

Two other wrecks were reported Sunday morning in Florence County and Dorchester, where Johnny Carl Floyd, 47, of Summerville died after crossing the center center line with a beer between his legs and other cold beers in the vehicle, according to highway officials.